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Physiological Gynecomastia and the Risk of Male Breast Cancer


Gynecomastia is defined as the benign hypertrophy of the male mammary glands, usually caused by abnormal hormonal changes in the body.

Gynecomastia occurrence within specific age groups

* Over 65% of male newborns (up to 90%) present increased mammary tissue, due to transfer of maternal and placenta hormones – the symptoms naturally receding after a few weeks.

* At ages 12 – 14, about 60% of the boys get gynecomastia, usually generated by a slow or delayed release of testosterone in the body, a temporary increase of aromatase (an enzyme which acts as a catalyst for the conversion of testosterone into estradiol) or a sensitivity towards estrogens. As puberty hits, sudden releases of several specific growth hormones stimulate testosterone production and gynecomastia disappears naturally, within a time frame of one or two years.

* Between the ages of 16 to 20,  the percentage lowers to 19%, followed by an increase up to 40% for male patients aged between 25 and 45.

* About 60% of the men above 50 years old present increased mammary tissue, due to declining testosterone levels.

Mammary hypertrophy caused by fat tissue (in case of obesity) is called pseudogynecomastia and it’s treated with workout, fat burning pills or liposuction.

Non physiological gynecomastia

This type of gynecomastia is generally associated with diseases or medication that go along with low testosterone levels, an accented conversion of testosterone into estrogen, high levels of estrogen.

Body builders who use high amounts of androgens (the enzyme aromatase will convert testosterone into estrogen).

Patients who are in treatment for prostate cancer have a higher predisposition for developing gynecomastia (up to 60%), while those who are in treatment for benign prostate hypertrophy are almost in the clear (about 1%).

A high amount of estrogens can be found in certain creams, body lotions and other types of cosmetics. Other products known to trigger gynecomastia are based on lavender oil and tea tree, because they contain substances that inhibit androgens. It takes only a couple of months for the symptoms to disappear, once the usage of those products has been interrupted.

Diagnosing gynecomastia and further medical investigations

The diagnosis is made taking in consideration multiple factors:

– a physical exam, where the physician pays attention to the size and consistency of the mammary tissue, possible nipple retraction, nipple pain, mammary secretion, axillary adenopathy – which could indicate the presence of breast cancer.

– history – lump growth speed, any association with liver or kidney illnesses, hyperthyroidism, testicular insufficiency, family history of gynecomastia and/or breast cancer.

Patients with physiological, pubertal or asymptomatic gynecomastia don’t need further medical investigation, although a reevaluation is recommended after six months.

However, a more in-depth evaluation is necessary for those patients who:

– present macromastia (lumps bigger than 5 cm);

– experience tenderness, pain;

– notice nipple retraction, mammary secretions;

– have noticed an accelerated growth of the mammary tissue;

-have discovered the presence of hard lymph nodes.

The usual procedures are mammography, breast biopsy, testicular and breast ultrasound and specific laboratory tests.

Physiological Gynecomastia

Male breast cancer is a rare disease – less than 1% of all breast cancer cases are related to men.

Some of the risk factors are:

– growing old – the average age for men with breast cancer has been established around 68 years old;

– high estrogen levels (due to hormonal medication, obesity, estrogen exposure from food, cosmetics, certain body building food supplements, liver dysfunction);

– Klinefelter syndrome (double or multiple X chromosomes and a single Y chromosome instead of the normal single X, single Y chromosomes specific to male DNA);

– family history of breast cancer;

– radiation exposure – for instance, radiation therapy to the chest in order to treat Hodgkin’s disease for patients under 30 years old or other types of radiation, for long periods of time.

Symptoms of male breast cancer:

–  nipple pain, nipple retraction; soreness or discoloration in the nipple area;

– mammary secretion;

– large or hard lymph nodes under the arm.

If the mammogram and/or breast ultrasounds have indicated the possibility of cancer, a biopsy will be performed. If the cancer has been certified, further tests will be done in order to determine the type and stage of cancer.


Treatment for male breast cancer

The treatment is the same as for female patients; it depends on the stage of development – which refers to its size and whether it has already spread or not, at the moment of the diagnose.

The usual procedures are:

surgery – the removal of the breast (mastectomy);

– chemotherapy – after surgery, in certain circumstances (the patient is young; the tumor was larger than 2 cm; cancer cells present in the lymph nodes);

– radiotherapy – also after surgery, to reduce the risk of the cancer coming back;

– hormone therapy if the tests have shown that the cancer cells have hormone receptors;

– biological therapy if the tests show the cancer cells to have HER2 receptors (human epidermal growth factor receptor 2).

Because male breast cancer is a rare occurrence, men usually aren’t aware of its possibility. There is an objective need for an increased public awareness of male breast cancer – ignorance causes a high rate of mortality among male patients with breast cancer, because the diagnosis is made too late, when the tumors are large and after the cancer has spread in the body.

As it holds good for all cancer types, the sooner it is discovered, the higher chances are that treatment may prove successful.

Therefore, regular checkups are important – keep in touch with your physician and make sure you let them know about any irregularity in the breast area – or under the arm (lumps, pains, hard tissue as presented above).

Treating Gynecomastia – Pills or Surgery?


Gynecomastia is referred to as a fat problem (mostly excessive fat) in the chest for men. It causes the breasts to appear awkwardly larger than normal. It is mainly due to fat production in the chest region which can happen during puberty and even in the later stages.

Gynecomastia –A Concern for Men

If you have seen any man with reasonably heavy chests, they are actually the ones suffering from Gynecomastia. If you know anyone close to you suffering from the problem, you would understand how difficult it is for them to face public. A good percentage of people turn introverts and cut off their social engagements to a certain degree due to their awkward looking chest. Some of them try to conceal it in several layers so that they can avoid public embarrassment. Nevertheless, it does affect a person psychologically.

Treatment For Gynecomastia

The good news is, Gynecomastia treatments are now commonly available. Mainly, there are two different modes of treatment. You can either opt for a surgery or you can go for oral treatment through pills. Confused about which way to go? Here you will find out a comparison between these two treatment modes to let you decide what works best for you.

We will look at different aspects of treatment and see what is the best for you.

Cost: Pills vs Surgery

Gynecomastia surgery can be quite costly. Depending on how large the tissue is, it can cost you as much as $7000 to get rid of excessive chest fat. In comparison to surgery, gynecomastia pills are nowhere near as expensive. Gynexin, which is the most widely used pill for chest fat reduction costs around $70 per bottle so you should probably give it a try before getting those cut marks on the chest.

Side Effects: Pills vs SurgeryGynecomastia Pills

Although surgeries do not have any side effects yet you will always be reminded of your problem in the future. It is because surgery marks and scars will be there on your chest all the way. Unless you are willing to spend extra money to get rid of these marks which quite frankly, is just a waste of time and money, these ‘leftovers’ of surgery will always recall your dark and depressing times with gynecomastia.

With Gynexin pills, there won’t be any such side effects at all. Once you get rid of the fat, you won’t even remember if you had any such problem before. Gynexin has been formulated with naturally active ingredients that have no side effects at all. These pills are legal and approved so it’s a safe bet going for pills rather than surgery.

What is More Effective?: Pills vs Surgerygynecomastia surgery

As far as surgery is concerned, the surgeon will only remove excessive fat from your chest. The chances of recurrence of Gynecomastia are minimal but you cannot rule out its possibility. Pubertal Gynecomastia doesn’t recur but if it happened to you in older age, there are chances it can happen to you again.

Considering how much a surgery can cost with very few but possible chances of recurrence, it is surely an expensive deal going for surgery. On the other hand, Gynexin treatment has been found to have permanent results. Once you get rid of chest fat, it won’t be coming back. It is actually because Gynexin addresses to the core causes of fat production rather than just reducing it down.

Pain Factor and Recovery: Pills vs Surgery

Surgeries have become lesser painful with time. However, you will have to go through a little bit of it to relieve of chest fat. Normally you can recover pain after surgery within a day or two from but there’s still two weeks’ time before you can hit the gym. Also, you will be wearing a compression strap for a few weeks for quicker healing.

On the other hand, with Gynexin pills, your routine is not disturbed one bit. You can workout and eat whatever you like. There is no requirement of prescription and consumption is also quite simple. You will need to take three pills a day i.e. one after every meal. Results appear within a week and there’s no need to continue with the pills after healing.


Having seen the comparison between the two modes of treatment, it won’t be too difficult for you to choose Gynexin pills ahead of surgery. It will save you time, money, effort and also the results are much better. So to avoid the hassles of scheduling an appointment with your surgeon and going through the pains of surgery, Gynexin is a useful and in fact better substitute to get rid of Gynecomastia.